Research is the cornerstone for scientific discovery. Seattle BioMed scientists are experts in the field of research, proven by hundreds of projects that provide the engine for discoveries. These projects represent new knowledge leading to scientific and technological breakthroughs and real-world applications.

Our Results

Seattle BioMed’s work results in breakthroughs that help people right here in Seattle, as well as on six continents around the world. Among our recent accomplishments are:

• Created a genetically attenuated (weakened) whole-organism malaria vaccine that is being tested in humans in 2010.
• Constructed a state-of-the-art Malaria Clinical Trials Center—one of only four in the world—within our labs to safely test malaria vaccine and treatment candidates.
• Developed the Seattle Structural Genomics Center for Infectious Disease (SSGCID), which recently determined the 100th three-dimensional protein structure from a number of bacterial and protozoan pathogens, which could potentially lead to new drugs, vaccines and diagnostics for emerging or re-emerging infectious diseases.
• Completed and published the genome sequences for T. cruzi, L. major and T. brucei, followed by a comparative analysis of these three parasites, as part of an international collaborative effort.
• Developed novel approaches to design vaccine candidates capable of eliciting effective neutralizing antibodies against HIV.
• Developed and commercially licensed pre-rRNA-based molecular viability tests for pathogens in clinical and environmental samples.

Seattle BioMed is continuously pioneering new advances in infectious disease research. Read more about us in the news to learn about our Institute’s progress.