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Scientific Research Publications

2010

The UPC2 promoter in Candida albicans contains two cis-acting elements that bind directly to Upc2p, resulting in transcriptional autoregulation
Hoot SJ, Brown RP, Oliver BG, White TC.

Eukaryot Cell

Increased CD4+ T Cell Levels during IL-7 Administration of Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Positive Macaques Are Not Dependent on Strong Proliferative Responses
Leone A, Rohankhedkar M, Okoye A, Legasse A, Axthelm MK, Villinger F, Piatak M Jr, Lifson JD, Assouline B, Morre M, Picker LJ, Sodora DL.

J Immunol.

Design and synthesis of nonpeptidic, small molecule inhibitors for the Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.
Rawls KA, Grundner C, Ellman JA.

Org Biomol Chem.

Alterations in the Immunogenic Properties of Soluble Trimeric Human Immunodeficiency Type-1 Envelope Proteins Induced by Deletion or Heterologous Substitutions of the V1 Loop.
Ching L, Stamatatos L.

J. Virol
Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques
Harris LD, Tabb B, Sodora DL, Paiardini M, Klatt NR, Douek DC, Silvestri G, Müller-Trutwin M, Vasile-Pandrea I, Apetrei C, Hirsch V, Lifson J, Brenchley JM, Estes JD.

J Virol

Biological and structural characterization of a host-adapting amino Acid in influenza virus
Yamada S, Hatta M, Staker BL, Watanabe S, Imai M, Shinya K, Sakai-Tagawa Y, Ito M, Ozawa M, Watanabe T, Sakabe S, Li C, Kim JH, Myler PJ, Phan I, Raymond A, Smith E, Stacy R, Nidom CA, Lank SM, Wiseman RW, Bimber BN, O'Connor DH, Neumann G, Stewart LJ, Kawaoka Y

PLoS Pathogens
Fidelity of Pathogen-Specific CD4(+) T Cells to the Th1 Lineage Is Controlled by Exogenous Cytokines, Interferon-gamma Expression, and Pathogen Lifestyle
 Curtis, MM, E Rowell, S Shafiani, A Negash, KB Urdahl, CB Wilson and SS Way

 

Cell Host Microbe

 

Hairpin dsRNA does not trigger RNA interference in Candida albicans cells
  Staab,JF, White TC, Marr KA

Yeast

Direct, help-independent priming of CD8+ T cells by adeno-associated virus-transduced hepatocytes
Wuensch SA, Spahn J, Crispe IN

Hepatology

3-Methyladenine blocks Toxoplasma gondii division prior to centrosome replication
Wang Y, Karnataki A, Parsons M, Weiss LM, Orlofsky A

Mol Biochem Parasitol

Characterization of a Clp Protease Gene Regulator and the Reaeration Response in Mycobacterium tuberculosis
Sherrid AM, Rustad TR, Cangelosi GA, Sherman DR

PLoS One

Acquired antibody responses against Plasmodium vivax infection vary with host genotype for duffy antigen receptor for chemokines (DARC)
Maestre A, Muskus C, Duque V, Agudelo O, Liu P, Takagi A, Ntumngia FB, Adams JH, Sim KL, Hoffman SL, Corradin G, Velez ID, Wang R

PLoS One

The Fe/S cluster assembly protein Isd11 is essential for tRNA thiolation in Trypanosoma brucei.
Paris Z, Changmai P, Rubio MA, Zikova A, Stuart KD, Alfonzo JD, Lukes J.

J Biol Chem

Multiple pH measurement during storage may detect bacterially contaminated platelet concentrates
Barker LM, Nanassy OZ, Reed MW, Geelhood SJ, Pfalzgraf RD, Cangelosi GA, de Korte D

Transfusion

Diverse Effects on Mitochondrial and Nuclear Functions Elicited by Drugs and Genetic Knockdowns in Bloodstream Stage Trypanosoma brucei
Worthen C, Jensen BC, Parsons M.

PLoS Neglected Tropical Diseases

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors
Ojo KK, Larson ET, Keyloun KR, Castaneda LJ, Derocher AE, Inampudi KK, Kim JE, Arakaki TL, Murphy RC, Zhang L, Napuli AJ, Maly DJ, Verlinde CL, Buckner FS, Parsons M, Hol WG, Merritt EA, Van Voorhis WC.

Nature Structural & Molecular Biology

Virus-specific CD8+ T-cell responses better define HIV disease progression than HLA genotype.
Dinges, W. L., J. Richardt, D. Friedrich, E. Jalbert, Y. Liu, C. E. Stevens, J. Maenza, A. C. Collier, D. E. Geraghty, J. Smith, Z. Moodie, J. I. Mullins, M. J. McElrath and H. Horton

Journal of Virology
Over-expression of TUF1 restores respiratory growth and fluconazole sensitivity to a C. neoformans vad1{Delta} mutant.
Panepinto JC, Misener AL, Oliver BG, Hu G, Park YD, Shin S, White TC, Williamson PR.

Microbiology

The Trypanosoma brucei Life Cycle Switch TbPTP1 Is Structurally Conserved
and Dephosphorylates the Nucleolar Protein, NOPP44/46
Chou S, Jensen BC, Parsons M, Alber T, Grundner C.

Journal of Biological Chemistry

Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in non-human primates
Engram JC, Cervasi B, Borghans JA, Klatt NR, Gordon SN, Chahroudi A, Else J, Mittler RS, Sodora DL, de Boer RJ, Brenchley JM, Silvestri G, Paiardini M

Blood