Seattle BioMed

A tense time for the nuclear envelope

Authors: 

Aitchison JD, Rout MP

Journal: 

Cell

Publication date: 
February 2002

When many cells divide, the nuclear envelope poses a problem: the spindle microtubules can't access the chromosomes. Two recent papers in Cell describe how the spindle solves this problem by literally pulling open the nucleus at the beginning of mitosis.